Preoperative deep venous thrombosis in female patients with lower extremity fracture in menstrual phase
10.3760/cma.j.issn.1671-7600.2018.08.011
- VernacularTitle:月经期女性下肢骨折术前发生深静脉血栓形成的研究
- Author:
Chen WANG
1
;
Zhe SONG
;
Pengfei WANG
;
Lisong HENG
;
Binfei ZHANG
;
Na YANG
;
Ding TIAN
;
Yangjun ZHU
;
Kun ZHANG
Author Information
1. 710000,西安医学院
- Keywords:
Menstruation;
Bones of lower extremity;
Fracture,bone;
Thrombosis
- From:
Chinese Journal of Orthopaedic Trauma
2018;20(8):696-699
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the factors associated with preoperative deep venous thrombosis (DVT) in female patients with lower extremity fracture in menstrual phase.Methods A retrospective analysis was conducted of the 119 women with lower extremity fracture in childbearing age who had been treated at Traumatic Orthopaedics Center,Red Cross Hospital,Xi'an Jiaotong University Health Science College from October 2016 to October 2017.Of them,41 were in menstral phase,aged from 20 to 50 years (average,37.1 ± 8.9 years),and 78 were not,aged from 19 to 50 years (average,36.9 ± 8.0 years).The 2 groups were compared in terms of DVT incidence,D-dimer level,prothrombin time,partial prothrombin time,thrombin time,fibrinogen level,and preoperative bed time.Results The patients with menstruation had significantly higher incidence of lower extremity DVT (82.9％) and significantly longer preoperative bed time (9.1 ± 3.4 d) than those without menstruation did (14.1％ and 3.8 ± 2.2 d,respectively) (P ＜0.05).There were no significant differences between the 2 groups in the preoperative coagulation indexes:D-dimer,prothrombin time,partial prothrombin time,thrombin time or fibrinogen (P ＞ 0.05).Conclusions The incidence of preoperative DVT may be high the female patients with lower extremity fracture in menstrual phase,chiefly because of long preoperative bed time.Detection of D-dimer level is of limited significance in the screening for thrombosis in menstrual phase.Menstruation may not be a surgical contraindication.
