Study on Ambi-extracting and Inclusion Process of Volatile Oil from Chuanxiong Rhizoma and Angelicae Sinensis Radix
10.3969/j.issn.1005-5304.2018.11.015
- VernacularTitle:川芎、当归双提法提取工艺及挥发油包合工艺研究
- Author:
Mei-Ling WANG
1
;
Jian NI
;
Lin GUO
;
Gong-Sen CHEN
;
Ying-Chao YU
;
Long-Tai YOU
;
Hai-Ying ZHANG
;
Xing-Bin YIN
;
Chang-Hai QU
Author Information
1. 北京中医药大学中药学院
- Keywords:
Chuanxiong Rhizoma;
Angelicae Sinensis Radix;
ferulic acid;
ambi-extracting;
β-CD;
inclusion process
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2018;25(11):68-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize ambi-extracting and inclusion process of volatile oil from Chuanxiong Rhizoma and Angelicae Sinensis Radix. Methods With yield ratio of volatile oil and ferulic acid content in water extract as evaluation indexes, single factor experiments were used to study the extraction process. With the inclusion rate of volatile oil and yield of inclusion as evaluation indexes, saturated aqueous solution was used to L9(34) orthogonal experiments to reach optimum inclusion process. Results The optimum extraction process of Chuanxiong Rhizoma and Angelicae Sinensis Radix was extracted for 8 hours with 8 folds the amount of water, and without soaking. The validation experiments of extraction of volatile oil and ferulic acid content in water extract were 1.23 mL and 0.387 9 mg/g. The optimum conditions of inclusion process were as follows: volatile oil (mL): β-CD (g) was 1:8;inclusion temperature was 40 ℃; inclusion time was 3 hours. The validation experiments of inclusion rate of volatile oil and yield of inclusion were 74.89% and 72.81%. Conclusion Optimum ambi-extracting and inclusion process of volatile oil from Chuanxiong Rhizoma and Angelicae Sinensis Radix are feasible and stable, witch can provide certain supporting data for preparation production.
