Research Progress in TCM Promoting the Development of Cerebral Ischemia Angiogenesis

VernacularTitle:中药促进脑缺血血管生成研究进展
Author: Sheng-Hui HUANG ¹ ; Yan-Yi LI ; Ting GONG
Author Information

1. 甘肃中医药大学中西医结合学院
Keywords: TCM; cerebral ischemia; angiogenesis; VEGF; Notch signaling pathway; Wnt signaling pathway; review
From: Chinese Journal of Information on Traditional Chinese Medicine 2018;25(7):137-140
CountryChina
Language:Chinese
Abstract: The promotion or inhibition of blood vessels by TCM, active ingredients of TCM, TCM compounds, and Chinese patent drugs is currently a research hotspot, with relatively abundant research. However, the study of the role and profound mechanism of TCM on angiogenesis after cerebral ischemia is relatively rare. Therefore, this article reviewed theories, in vitro studies and in vivo studies on the promotion of cerebral angiogenesis by TCM, and summarized the studies on TCM regulation of angiogenesis through Notch and Wnt signaling pathway mechanisms, with a purpose to provide references for resarch on related mechanisms and development of new deugs.