Optimization of Extraction Technology for Yangxin Anshen Granules with Orthogonal Test
10.3969/j.issn.1005-5304.2018.07.019
- VernacularTitle:正交试验优化养心安神颗粒提取工艺
- Author:
Li-Ping CAO
1
;
Qi LIANG
;
Shu-Guang LI
;
Yue XIE
;
Zi-Long ZHANG
;
Guang-Yi YANG
Author Information
1. 深圳市宝安中医院(集团)
- Keywords:
Yangxin Anshen Granules;
volatile oil;
paeoniflorin;
total solid;
HPLC;
orthogonal test;
extraction technology
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2018;25(7):79-82
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction technology for Yangxin Anshen Granules. Methods With yield of volatile oil as index, single factor tests were adopted to investigate effects of water, soaking time and distillation time on extraction technology of volatile oil. Using water amount, extraction time and extraction times as factors, the contents of paeoniflorin and total solid as indexes, orthogonal test was employed to optimize the extraction technology of Yangxin Anshen Granules. Results The optimical extraction technology conditions were as follows:Cinnamomi Ramulus, Saposhkoviae Radix, and Citri Sarcodactylis Fructus were extracted to get volatile oil with eight-folds amount water of herbs for 6 hours; other herbs were boiled with eight-folds amount water of herbs and extrancted for two times, 1 h each time. Conclusion This extraction process is reasonable and practical, and can well guarantee the quality of preparation.
