Clinical Study on Effects of Modified Dachaihu Decoction on Treatment of Constipation in Hemodialysis Patients
10.3969/j.issn.1005-5304.2018.06.008
- VernacularTitle:大柴胡汤加味治疗维持性血液透析便秘患者临床研究
- Author:
Yue LIN
1
;
Yu LI
Author Information
1. 北京王府中西医结合医院
- Keywords:
maintenance hemodialysis;
constipation;
Dachaihu Decoction
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2018;25(6):30-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of modified Dachaihu Decoction on the treatment of constipation in hemodialysis patients. Methods Totally 60 hemodialysis patients were divided into treatment group and control group through random number table method, with 30 cases in each group. Both groups received Western basic treatment. The treatment group was given modified Dachaihu Decoction on the basis of Western medicine treatment,one dosage 100 mL per day,morning and evening after dinner,orally.The control group received Maren Runchang Pills, one pill each time, twice a day, orally. The treatment cycle for both groups was one month. The clinical efficacy, constipation symptoms, incidence of hypotension during dialysis, incidence of muscle spasm and Kt/V were compared between the two groups. Results The total effective rate was 93.33% (28/30) in the treatment group and 66.67% (20/30) in the control group. The treatment group was significantly better than the control group (P<0.05). Compared with before treatment, the number of defecation per week increased after treatment in both groups, and the squatting time decreased; Comparing the two groups after treatment, the number of defecation per week and squatting time in the treatment group were significantly better than those in the control group (P<0.05). Compared with before treatment, the incidence of hypotension rate in the treatment groups of dialysis were significantly reduced (P<0.05); After treatment, the incidence of hypotension in the treatment group was significantly lower than those in the control group (P<0.05). Compared with before treatment, Kt/V in both groups increased significantly (P<0.05); After treatment, the improvement of Kt/V in the treatment group was significantly better than that in the control group(P<0.05).Conclusion Modified Dachaihu Decoction can effectively improve the symptoms of hemodialysis patients with constipation and improve the dialysis adequacy.
