Advances of research in cancer-associated inflammation and tumor microenvironments
10.3969/j.issn.1000-8179.2018.21.767
- VernacularTitle:癌症相关性炎症与肿瘤微环境相关研究进展
- Author:
Zhimin WEI
1
;
Yufa SUN
;
Gang LI
;
Zhefeng LIU
Author Information
1. 中央军委联合参谋部警卫局卫生保健处 北京市100017
- Keywords:
cancer-associated inflammation;
cytokine network;
tumor immunology;
tumor microenvironment (TME)
- From:
Chinese Journal of Clinical Oncology
2018;45(21):1117-1121
- CountryChina
- Language:Chinese
-
Abstract:
Cancer-associated inflammation is one of the key features of cancer. Many cytokines are involved in inflammation and its regulation and play important roles in many factors affecting tumor biology. Inflammation participates in the construction of tumor mi-croenvironments (TMEs) by changing the homeostasis of tumor tissues. The interaction of cytokines secreted by TME-infiltrating cells forms a complex network of cytokines that play a role in tumor progression through various mechanisms such as inflammation promo-tion, immune editing, and immune escape. This review aims at analyzing the research progress on the relationship between inflamma-tion, cytokine networks, and TMEs
