Analysis of non-tumor diseases affecting the diagnosis and treatment of cancer patients
10.3969/j.issn.1000-8179.2018.10.161
- VernacularTitle:影响恶性肿瘤诊治的非肿瘤性疾病分析
- Author:
Sen HAN
1
;
Wei LI
;
Jian FANG
;
Jun NIE
;
Ling DAI
;
Weiheng HU
;
Xiaoling CHEN
;
Jie ZHANG
;
Xiangjuan MA
;
Guangmin TIAN
;
Di WU
;
Jieran LONG
;
Jindi HAN
;
Yang WANG
;
Ziran ZHANG
;
Weiping LIU
;
Jun ZHU
Author Information
1. 北京大学肿瘤医院暨北京市肿瘤防治研究所
- Keywords:
cancer;
non-tumor disease;
cardio-oncology
- From:
Chinese Journal of Clinical Oncology
2018;45(10):517-520
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the types of non-tumor diseases in patients with cancer, and to explore the effects of those dis-eases on the diagnosis and treatment of cancer patients. Methods:We collected the medical records of cancer patients from January 2013 to December 2017 in Peking University Cancer Hospital, and screened for non-tumor diseases. The clinical records of the patients in this group were analyzed retrospectively, and the effects of those diseases on the diagnosis and treatment of tumors were dis-cussed. Results:Of the 1,323 cases of inter-hospital consultation, 1,153 cases of non-tumor disease (87.2%) were selected. There were 773 men (67.0%) and 380 women (33.0%) included. The median age was 62 (14-90) years. The primary tumor types included lung can-cer, gastric cancer, lymphoma, colorectal cancer, esophageal cancer, breast cancer, malignant melanoma, liver cancer, cholangiocarci-noma/gallbladder cancer, pancreatic cancer, and other tumors. Non-neoplastic diseases included cardiovascular disease in 356 cases (30.9%), respiratory system disease (17.0%) in 196 cases, digestive system disease in 107 cases (9.3%), skin and venereal diseases in 81 cases (7.0%), nervous system lesions (6.4%) in 74 cases, urinary system disease in 72 cases (6.2%), blood disease in 70 cases (6.1%), en-docrine and metabolic diseases in 47 cases (4.1%), autoimmune disease in 23 cases (2.0%), and other diseases (11.0%) in 127 cases. Impact on tumor diagnosis and treatment was as follows:direct, 771 cases (66.9%);no influence, 313 cases (27.1%);and uncertain, 69 cases (6.0%). Conclusions:Cardiovascular disease is a major non-tumor disease associated with cancer. Non-neoplastic diseases are important factors affecting the diagnosis and treatment plans of cancer.