The effect of different excision methods on the prognosis of type Ⅲ and Ⅳ hilar chol-angiocarcinoma
10.3969/j.issn.1000-8179.2018.05.157
- VernacularTitle:Ⅲ Ⅳ型肝门胆管癌不同切除方式对预后的影响
- Author:
Xiaoqing WANG
1
;
Feng FANG
;
Guangtao LI
;
Hongying HE
;
Tianqiang SONG
Author Information
1. 天津医科大学肿瘤医院肝胆肿瘤科
- Keywords:
cholangiocarcinoma hepatectomy;
resection rate;
postoperative complications;
prognosis
- From:
Chinese Journal of Clinical Oncology
2018;45(5):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the relationship between the operative strategies and clinical outcomes of type Ⅲ and Ⅳ hilar chol-angiocarcinomas(HCs).Methods:We retrospectively analyzed the clinical data and long-term outcomes for 50 cases of type Ⅲ and Ⅳ HC that underwent surgery at the Tianjin Medical University Cancer Hospital.Results:Fifty patients were followed up and the median follow-up duration was 27 months.The hilar limited hepatectomy group included 13 cases;the median disease-free survival was 6 months,and 1-and 2-year disease-free survival rates were 30.8% and 23.1%,respectively.The median overall survival was 20 months, and the 1-and 2-year overall survival rates were 76.9% and 38.5%,respectively.The extended hepatectomy group included 37 cases;the median disease-free survival was 14 months,and 1-and 2-year disease-free survival rates were 59.5% and 32.4%,respectively.The median overall survival was 37 months,and the 1-and 2-year overall survival rates were 83.8% and 51.4%,respectively.Compared with the hilar limited hepatectomy group,the extended hepatectomy group had significantly longer median disease-free and overall survival(P<0.05).The 1-and 2-year disease-free and overall survival rates were higher for the extended hepatectomy group.There was no significant difference in morbidity and mortality between the two groups(P>0.05).Conclusions:Extended hepatectomy is a safe operation that delays recurrence at early time points and improves the prognosis for patients with type Ⅲ and Ⅳ HC.
