Clinical analysis of clear cell sarcoma of the kidney in children
10.3969/j.issn.1000-8179.2017.24.852
- VernacularTitle:儿童肾透明细胞肉瘤的临床分析
- Author:
Feng LIU
1
;
Qiang ZHAO
;
Jie YAN
;
Jingfu WANG
;
Zhanglin LI
;
Yanna CAO
;
Jie LI
;
Wenfeng CAO
Author Information
1. 天津医科大学肿瘤医院儿童肿瘤科
- Keywords:
clear cell sarcoma of the kidney;
chemotherapy protocol;
efficacy;
child;
prognosis
- From:
Chinese Journal of Clinical Oncology
2017;44(24):1258-1261
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the clinical features of clear cell sarcoma of the kidney (CCSK) in children and to evaluate the effica-cy and safety of the WT-2009 chemotherapy protocol. Methods:Clinical data of children with CCSK recorded between January 2009 and December 2014 were retrospectively analyzed. Follow-ups were conducted to monitor the postoperative conditions of the pa-tients. Results:Nine cases of CCSK were recruited, and another three cases were excluded for the analysis because of incomplete clini-cal data. All patients achieved complete remission when the treatment was finished. The estimated 3-year overall survival rate was 100％, and the estimated 3-year event-free survival rate was 83.3％. No report is available on the significant side effects associated with this treatment. Conclusion:CCSK is rare in children and is easily misdiagnosed. The chemotherapy based on the WT-2009 proto-col can produce a favorable prognosis and a high tolerance for patients with CCSK. However, the treatment for high-risk patient needs to be further explored, and follow-ups must be intensified.
