From infection to immunotherapy:the immune response of bladder mucous membrane to host

VernacularTitle:从感染到免疫治疗:膀胱黏膜对宿主的免疫应答
Author: Su CHEN ¹ ; Yulong TAN ; Kehua JIANG ; Hongbo CHEN
Author Information

1. 445000,湖北省恩施土家族苗族自治州中心医院泌尿外科
Keywords: Bladder mucosa; Immunity; BCG vaccine; Urinary tract infection; Bladder cancer
From: Clinical Medicine of China 2018;34(6):573-576
CountryChina
Language:Chinese
Abstract: Objective The pathogenesis of urinary tract infection and the preventive effect of Bacillus Calmette Guerin on bladder cancer imply the importance of bladder as a unique mucosal surface research. This article discussed that after bladder infected by bacteria,the way in which the microenvironment produce adaptive immunity. Once in the past, bladder is widely considered to be a sterile environment, the concept has been recently shaken. It is suggested that we should further study the influence of urinary tract pathogen infection or BCG immune response. In this paper, bladder biology has been illustrated, and bladder organ immunity is urgently needed to be explored and defined.