Clinical analysis of 72 cases of bacterial meningitis in infants under 6 months old
10.3760/cma.j.issn.1008-6315.2018.03.019
- VernacularTitle:6月龄以下婴儿72例细菌性脑膜炎临床分析
- Author:
Luohui LIU
1
;
Minghui QIU
Author Information
1. 518028,广东省深圳市妇幼保健院儿科
- Keywords:
Bacterial meningitis;
Infants;
Under 6 months old;
Subdural effusion
- From:
Clinical Medicine of China
2018;34(3):277-280
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical characteristics and treatment outcome of infants with bacterial meningitis (BM) under 6 months.Methods Seventy-two cases of infants with BM under 6 months were retrospectively analyzed.Among them,the infants of age ranging from 29 days to 30 days were assigned into the 1 month age group,60 days to 179 days infants were assigned into the 2 to 5 months old group.Results The incidence of BM was more common in male (51 cases,70.8%) and infants with the age of 1 month (45 cases,62.5%).The clinical manifestations included fever (71 cases,98.6%),procalcitonin increase (55 cases,76.3%),respiratory tract infection (48 cases,66.6%),peripheral blood WBC count abnormal results (34 cases,47.3%),abnormal blood CRP (20 cases,27.8%) and nervous system abnormalities (18 cases,25%).Among the 1 month old group,12 infants had urinary tract infection (16.6%),and 6 had convulsions (8.3%).There were 4 cases (5.5%) with subdural effusion in the 2 ~ 5 months old group.Compared with the 2 ~ 5 months old group,the 1 month old group was more likely to be caused by urinary tract infection,more prone to seizures,the difference was statistically significant (x2 =3.996,3.927,P<0.05).Compared with the 1 month old group,the 2 ~ 5 months old group was more prone to subdural effusion,and the peripheral blood white blood ceils was higher,the difference was statistically significant (x2 =7.059,4.295,P<0.05).Conclusion There is no obvious clinical manifestation or laboratory examination for infants under 6 months old BM,so it is necessary to make early cerebrospinal fluid examination for early diagnosis and early treatment.