New progress in the early screening of cervical precancerous lesions
10.3760/cma.j.issn.1008?6315.2018.02.024
- VernacularTitle:宫颈癌前病变早期筛查技术新进展
- Author:
Jing WANG
1
;
Haizhu SUN
;
Aili XU
;
Xianchao KONG
Author Information
1. 150086,哈尔滨医科大学附属第二医院妇产科
- Keywords:
Cervical cancer;
Human papillomavirus;
Human telomerase gene;
DNA methylation
- From:
Clinical Medicine of China
2018;34(2):189-192
- CountryChina
- Language:Chinese
-
Abstract:
Cervical cancer is one of the most common gynecological malignancies which seriously threatens the health of women. How to further expand the scope of screening and improve the sensitivity and specificity of screening and optimize screening programs are the key points of cancer prevention and treatment. At present,the screening methods that are commonly used at home and abroad include cervical smear cytology, human papillomavirus ( HPV) detection,molecular biology detection and genetic genetic testing. Cervical smear cytology has high specificity and low sensitivity,the sensitivity of HPV detection is high,but the specificity is low,and the molecular biological detection and genetic testing has high specificity and high sensitivity,but due to the lack of large quantities of clinical samples,and the higher detection cost,they are still in the test study stage.
