Advances in the effect of adenosine A2 receptor activation in the prevention and treatment of ischemic diseases
10.3760/cma.j.issn.1008?6315.2018.02.019
- VernacularTitle:腺苷A2受体活化对缺血性疾病的防治作用研究进展
- Author:
Yahan SUN
1
;
Mali HE
;
Jingman XU
Author Information
1. 华北理工大学医学实验研究中心
- Keywords:
Adenosine;
Adenosine A2 receptor;
Adenosine A2 receptor agonist;
Ischemic disease
- From:
Clinical Medicine of China
2018;34(2):173-176
- CountryChina
- Language:Chinese
-
Abstract:
Adenosine,also known as adenine nucleoside,is an important bioactive substances. A large number of studies found that adenosine is involved in the prevention and treatment of many diseases by activating adenosine receptors. Up to now,Adenosine receptors have cloned four subtypes,such as A1,A2a,A2b and A3 and they can be combined with AD and start the downstream signal transduction mechanism,then have different effects on the body. This article will summarize the distribution and activation of adenosine A2 receptor and its role and mechanism in the prevention and treatment of disease.
