Surgical safety analysis of retained glands for micro-papillary thyroid carcinoma
10.3760/cma.j.issn.1008?6315.2018.02.012
- VernacularTitle:甲状腺微小乳头状癌行保留腺体的手术安全性分析
- Author:
Jianping LIU
1
;
Bin ZHAO
Author Information
1. 200137,上海中医药大学附属第七人民医院普外科
- Keywords:
Micro?papillary thyroid carcinoma;
Unilateral total lobectomy;
Complications
- From:Clinical Medicine of China
2018;34(2):149-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the surgical safety of retained glands for micro?papillary thyroid carcinoma(mPTC). Methods A total of two hundred patients with mPTC from June 2012 to June 2016 in Seventh People's Hospital of Shanghai University of TCM were enrolled in this study: single follow?up group (group A,40 cases),unilateral total lobectomy+isthmus resection group(group B,85 cases),unilateral total lobectomy+contralateral lobe subtotal resection group( group C,45 cases) ,bilateral total lobectomy ( group D,30 cases) ,then the clinical outcome was compared. Results The average follow?up time was about 26. 5 months, and there was no significant increase in tumor diameter in group A ( (6. 6±1. 5) mm vs. (6. 5±1. 3) mm,t=0. 326,P=0. 621) . The incidences of hypothyroidism in group B and C were significantly lower than that in group D ( 7. 1％ vs. 30. 0％,χ2 =8. 366, P=0. 004, 11. 1％ vs. 30. 0％,χ2 =4. 230, P= 0. 040 ) , while the differences in hypoparathyroidism,hypocalcemia,laryngeal nerve injury and total rate among group B,C and D were not statistically significant(P>0. 05). The median survival times in group B,C and D were significantly longer than that in group A (42. 2months,43. 5months,43. 6months vs. 32. 8months,P<0. 05),while there was no significant difference among group B,C and D ( P>0. 05) . There was no statistically significant difference in 3?year tumor mortality and recurrence rates among the three groups ( P>0. 05 ) . Conclusion Unilateral lobe resection + isthmus resection + ipsilateral central lymph node dissection can maintain the gland function,reduce complications,without reducing the survival,it is worthy of popularization and application.
