Multi-parameter Magnetic Resonance Imaging in the Diagnosis of Prostate Cancer: A Meta-analysis
10.3969/j.issn.1005-5185.2018.03.018
- VernacularTitle:多参数MRI对前列腺癌诊断价值的Meta分析
- Author:
Xiaofeng JIANG
1
;
Hongwei LI
;
Lang WANG
;
Licheng LEI
;
Chuan LIU
;
Li ZHU
;
Jun LIU
;
Yong DU
Author Information
1. 川北医学院附属医院放射科
- Keywords:
Prostatic neoplasms;
Magnetic resonance imaging;
Meta-analysis
- From:
Chinese Journal of Medical Imaging
2018;26(3):235-240
- CountryChina
- Language:Chinese
-
Abstract:
Purpose Meta-analysis of diagnostic value of prostate cancer (PCa) based on multi-parameter magnetic resonance imaging (mp-MRI). Materials and Methods Computer-based search of PubMed, Ebsco, Embase, Ovid, CBM, VPCS, Wanfang, and CNKI databases for related literatures on PCa diagnosed via mp-MRI from January 1, 2013 to September 31, 2017. Two researchers independently screened out literatures, extracted data based on inclusion and exclusion criteria, applied QUADAS-2 to evaluate the quality of methodologies included for the study, calculated combined sensitivity (Sen), specificity (Spe), positive likelihood ratio (+LR), negative likelihood ratio (-LR), and diagnostic odds ratio (DOR), drew Summerized receiver operating characteristic (SROC) curve and calculated the area under the curve (AUC). Results Eventually 20 articles of literatures were included, totally 3334 lesions. Meta-analysis results showed that Senmergeof PCa diagnosed via mp-MRI was 0.89(95% CI 0.87-0.92),Spemerge0.76(95% CI 0.67-0.84),+LRmerge3.8(95% CI 2.7-5.4),-LRmerge=0.14(95% CI 0.11-0.17),DORmerge=27(95% CI 17-44),AUCmerge=0.92(95% CI 0.89-0.94).Conclusion mp-MRI has a high diagnostic value for PCa and can be used as an important method for PCa diagnosis.
