99Tcm-MIBI Gated Myocardial Perfusion Imaging in Evaluating Coronary Microangiopathy in Patients with Diabetic Mellitus
10.3969/j.issn.1005-5185.2017.10.015
- VernacularTitle:99锝m-甲氧基异丁基异腈门控心肌灌注显像评估糖尿病患者冠状动脉微血管病变
- Author:
Qi ZUO
1
;
Tianfa LI
;
Jun WANG
;
Wen SUN
;
Huan XIAO
Author Information
1. 海南医学院心血管病研究所
- Keywords:
Diabetes mellitus;
Diabetic angiopathies;
Angina pectoris;
Coronary artery disease;
Coronary vessels;
Myocardial ischemia;
Gated blood-pool imaging;
Technetium 99Tcm sestamibi
- From:
Chinese Journal of Medical Imaging
2017;25(10):772-776
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the clinical guiding value of 99Tcm-methoxyisobutylisonitrile gated myocardial perfusion imaging (99Tcm-MIBI G-MPI) in diagnosing the coronary microangiopathy in patients with diabetic mellitus.Materials and Methods Sixty patients with clinical confirmed coronary microvascular angina were selected and assigned into two groups,with 26 patients (with diabetes mellitus) in group A and 34 patients in group B (without diabetes mellitus).The region,extent and range of coronary microangiopathy was detected by 99Tcm-MIBI G-MPI,and the difference of myocardial ischemia between the two groups was statistically analyzed.Results The ratio of abnormal myocardial perfusion in group A was significantly higher than that in group B (96.15％ vs.73.53％,x2=5.43,P＜0.05);the total number of abnormal coronary branches in group A was significantly larger than that in group B (82.67％ vs.62.67％,P＜0.05);the total number abnormal perfusion segments in group A was significantly larger than that in group B (P＜0.05),and the abnormal perfusion segments number of anterior wall,septum,apical region and inferior wall in group A was significantly larger than that ingroup B (P＜0.05);the rate of abnormal perfusion at single coronary supplying region in group A was significantly lower than that in group B (P＜0.05).Conclusion 99Tcm-MIBI G-MPI is of great clinical significance for diagnosing coronary microangiopathy and evaluating myocardial ischemia in patients with diabetes mellitus.
