Successful Treatment of Candida albicans Endocarditis with Liposomal Amphotericin B (AmBisome(R)) in a Very Low Birth Weight Infant.
- Author:
Hong Kyu PARK
1
;
Nam Ju SUNG
;
Me Jin KIM
;
Young Ho KIM
;
Ji A JUNG
;
Seung YANG
;
Il Tae HWANG
;
Hae Ran LEE
Author Information
1. Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea. ithwang83@hallym.or.kr
- Publication Type:Case Report
- Keywords:
Neonate;
Candida albicans;
Endocarditis;
Liposomal Amphotericin B
- MeSH:
Amphotericin B*;
Candida albicans*;
Candida*;
Candidemia;
Candidiasis;
Causality;
Endocarditis*;
Heart Defects, Congenital;
Humans;
Infant, Newborn;
Infant, Premature;
Infant, Very Low Birth Weight*;
Critical Care;
Survival Rate;
Thoracic Surgery
- From:Journal of the Korean Society of Neonatology
2006;13(1):184-188
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Candida albicans endocarditis is an uncommon manifestation of systemic candidiasis in newborn infants who require intensive care and develops mostly in patients with congenital heart disease; open heart surgery is the majority of predisposing factor. Improvement of techniques managing premature infants leads to increased survival rates, which give much more chances to develop fungal infections and its complications. We report a case of very low birth weight infant who had candidemia and Candida endocarditis, who was successfully treated with AmBisome(R) because of no response to conventional amphotericin B therapy.
