Single Index, Double Exponential and Tensile Density Index Model Diffusion Weighted Imaging in Diagnosis of Endometrial Carcinoma
10.3969/j.issn.1005-5185.2017.08.013
- VernacularTitle:单指数、双指数及拉伸指数模型扩散加权成像参数诊断子宫内膜癌
- Author:
Nan MENG
1
;
Ruifang YAN
;
Jipeng REN
;
Hongxia WANG
;
Xingxing JIN
;
Dongming HAN
Author Information
1. 新乡医学院第一附属医院核磁共振科 河南卫辉453100
- Keywords:
Endometrial neoplasms;
Magnetic resonance imaging;
Diffusion weighted imaging
- From:
Chinese Journal of Medical Imaging
2017;25(8):609-612,616
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To explore the application of single index,double exponential and tensile density index model diffusion weighted imaging and other parameters on endometrial carcinoma diagnosis to offer new ideas for it.Materials and Methods Intravoxel incoherent motion imaging data of 28 endometrial carcinoma patients and 24 patients of normal endometrium were analyzed retrospectively.Single index,double exponential and DWI parameter of endometrial carcinoma tissue and normal endometrial tissue were measured respectively,including standard apparent diffusion coefficient (ADC-stand),slow apparent diffusion coefficient (ADC-slow),fast apparent diffusion coefficient (ADC-fast,perfusion fraction (f),distributed diffusion coefficient (DDC) and a.Receiver operator characteristic (ROC) curve was adopted to assess threshold value and diagnostic efficiency of each parameter,and analyzed difference among each parameter in two groups and relativity of each parameter in the same group.Results ADC-stand,ADC-slow,f,DDC and a in endometrial carcinoma group were all lower than those in normal endometrium group.The difference was statistically significant (P＜0.05).The difference of ADC-fast was not statistically significant (P＞0.05).Areas of ADC-stand and ADC-slow on ROC curve were 0.949 and 0.911 respectively,and threshold values were 1.245×10-3 mm2/s and 0.998× 10-3 mm2/s.ADC-stand in endometrial carcinoma group was positive correlated with ADC-slow and DDC value (r=0.787 and 0.880,P＜0.05).ADC-slow was significantly lower than ADC-stand (P＜0.05).Conclusion The differences in single index,double exponential and DWI can provide new ideas for endometrial carcinoma diagnosis.
