ADC and relative ADC in differential diagnosis of lymphoma and metastasis in cervical lymph nodes
10.13929/j.1003-3289.201711020
- VernacularTitle:ADC值及相对ADC值鉴别诊断颈部淋巴瘤与转移性淋巴结
- Author:
Jing ZHONG
1
;
Cuifang CHEN
;
Ying CHEN
;
Jiahao LIN
;
Daoliang BAO
;
Yunbin CHEN
Author Information
1. 福建省肿瘤医院福建医科大学附属肿瘤医院放射诊断科
- Keywords:
Magnetic resonance imaging;
Lymphoma;
Apparent diffusion coefficient;
Lymphatic metastasis
- From:
Chinese Journal of Medical Imaging Technology
2018;34(6):846-849
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of MR apparent diffusion coefficient (ADC) and relative apparent diffusion coefficient (rADC) in differential diagnosis of lymphoma and metastasis in cervical lymph nodes.Methods Totally 69 patients with lymphoma (lymphoma group) and 66 patients with cervical lymph nodes metastasis (metastasis group) underwent MR examination.ADC values of lymph nodes and the right masseter muscle were measured,and rADC values were calculated.The consistency between two observers was evaluated.The differences of ADC value and rADC value were compared between the two groups.The efficacy of ADC value and rADC value in differential diagnosis of lymphoma and metastasis in cervical lymph nodes was analyzed with ROC curve.Results The consistency between two observers was excellent (all ICC＞0.9).Both ADC and rADC values of lymphoma group were significantly lower than those of metastasis group (all P＜0.05).Taken ADC and rADC values as 0.702 × 10-3 mm2/s and 0.584,the sensitivity and specificity was 98.48 ％ and 89.39 ％,76.81 ％ and 84.06 ％,respectively.Conclusion ADC and rADC values are useful in discriminating lymphoma from metastatic lymph nodes.
