Digital breast tomosynthesis for diagnosing non-calcified masses in dense breasts
10.13929/j.1003-3289.201702037
- VernacularTitle:数字乳腺断层摄影诊断致密型乳腺无钙化肿块
- Author:
Tiantian BIAN
1
;
Zengjie WU
;
Qing LIN
;
Chunxiao CUI
;
Lili LI
;
Xiaohui SU
;
Jie FEI
;
Feifei MENG
;
Congcong WANG
Author Information
1. 青岛大学附属医院乳腺影像科
- Keywords:
Breast diseases;
Mammography;
Ultrasonography;
Non-calcified mass
- From:
Chinese Journal of Medical Imaging Technology
2018;34(4):553-557
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical value of digital breast tomosynthesis (DBT) compared with digital mammography (DM) and ultrasound for diagnosing non-calcified masses in dense breasts.Methods Images taken with DBT,DM and ultrasound of 1144 patients with non-calcified masses in dense breasts were retrospectively analyzed using breast imaging reporting and data system (BI-RADS).Taking histopathologic results as golden standards,the detection rate and diagnostic accuracy,sensitivity,specificity,false negative and BI-RADS category were evaluated and compared statistically.Results The detection rate of DBT,DM and ultrasound for non-calcified massed in dense breasts was 86.62% (991/1 144),77.80% (890/1 144) and 99.65% (1 140/1 144),respectively (P<0.05),while the diagnostic accuracy was 83.92% (960/1 144),75.00% (858/1 144) and 94.67% (1 083/1 144),respectively (P<0.01).The sensitivity of DBT,DM and ultrasound was 89.39% (312/349),79.93% (231/289) and 92.70% (432/466),the specificity was 81.51% (648/795),73.33% (627/855) and 96.02% (651/678),while the false negative rate was 10.60%(37/349),20.07% (58/289) and 7.30% (34/466),respectively.No significant difference was found for benign lesions among three examination methods (P=0.75),while there was significant difference for malignant lesions among three examination methods (P<0.01),and the differences of ultrasonography with DM and DBT,DBT and DM in the for BI-RADS category of malignant lesions were statistically significant (all P<0.016 7).Conclusion For suspected masses in dense breasts,DBT shows significant advantage than DM,while DBT has the similar advantage compared with ultrasound for the detection and diagnosis of non-calcified masses in dense breasts.