Research progresses of resting-state functional MRI in patients of end-stage renal disease patients with cognitive impairment
10.13929/j.1003-3289.201709150
- VernacularTitle:终末期肾病患者认知功能损伤的静息态功能MRI研究进展
- Author:
Qing XIE
1
;
Li JING
;
Jianlin WU
Author Information
1. 大连大学附属中山医院放射科
- Keywords:
Kidney failure,chronic;
Cognitive dysfunction;
Magnetic resonance imaging;
Resting-state
- From:
Chinese Journal of Medical Imaging Technology
2018;34(3):448-451
- CountryChina
- Language:Chinese
-
Abstract:
End-stage renal disease (ESRD) is often complicated with damage of multi-organ function,among them,cognitive impairment has been noticed with a high prevalence.The abnormal intrinsic brain activity patterns in resting state is one of the manifestations of cognitive impairment in ESRD.Resting-state functional MRI (rs-fMRI) is divided into two categories,i.e.functional separation and functional integration,reflecting the changes of neural activity of the brain in different aspects.With advantages of non-invasive,no radiation and high spatio-temporal resolution,rs-fMRI has gradually become an effective method in studying the neurophysiological mechanisms of cognitive impairment.The pathophysiology and research progresses of rs-fMRI in ESRD with cognitive impairment were reviewed in this article.
