Optimization of scanning protocol in low-dose one-stop CT perfusion imaging combined with CTA of whole brain
10.13929/j.1003-3289.201706077
- VernacularTitle:优化低剂量一站式全脑CT灌注成像联合CTA扫描方案
- Author:
Jing JING
1
;
Yanwei MIAO
Author Information
1. 大连医科大学附属第一医院放射科
- Keywords:
Tomography,X-ray computed;
Brain;
Perfusion imaging;
Angiography
- From:
Chinese Journal of Medical Imaging Technology
2018;34(3):424-428
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize protocol in one-stop whole brain CT perfusion imaging (CTP) combined with CTA.Methods Totally 45 subjects underwent one-stop whole brain CTP combined with CTA with three different scanning protocols and 22 phases.CTA images were reconstructed from CTP original data at the tenth phase,the protocols of three scanning groups were as follows:Group A using automatic tube current modulation technique (ATCM) with low noise index (NI;NI=2),group B with fixed tube current (325 mA) and group C using ATCM with slightly low NI (NI=2.5),and the other phases of three groups were performed with ATCM and NI=8.Tube voltage of all three scanning protocols was 100 kV.The radiation dose and related parameters were recorded.Objective parameters including image noise (SD),SNR,CNR and perfusion parameters in different parts of the brain parenchyma and subjective scores of CTA,CTP image quality were compared among three groups.Results There was significant difference of effective dose (ED) among three groups (P＜0.05).ED of group A was higher than that of group B and C (P=0.043,0.001).No difference was found in CTA image noise,SNR,CNR nor subjective scores among three groups (P=0.218,0.545,0.575,0.900),neither of CTP images among three groups (P＞ 0.05).Conclusion Using ATCM and increasing NI appropriately may reduce radiation dose in one-stop CTP combined with CTA.
