CT manifestations of lung in Castleman disease

Jun Qiang; Diansen Chen; Lan Chen; Junxia Wang; Yongzheng Wang

Return

CT manifestations of lung in Castleman disease

VernacularTitle:巨大淋巴结增生症肺部CT表现
Author: Jun QIANG ¹ ; Diansen CHEN ; Lan CHEN ; Junxia WANG ; Yongzheng WANG
Author Information

1. 河南科技大学临床医学院河南科技大学第一附属医院影像科
Keywords: Giant lymph node hyperplasia; Lung; Tomography,X-ray computed
From: Chinese Journal of Medical Imaging Technology 2018;34(3):358-361
CountryChina
Language:Chinese
Abstract: Objective To explore CT manifestations of the lung in Castleman disease (CD) patients.Methods Totally 14 CD patients with abnormal pulmonary manifestations were enrolled,including 8 multicentric CD (MCD) and 6 unicentric CD (UCD).CT manifestations of the lung were analyzed retrospectively.Results In 3 patients of pulmonary hilar UCD,CT showed circular masses with solitary homogeneous density,obviously or markedly enhanced after contrast media administration.Bronchiolitis obliterans was found in 1 patient of retroperitoneal UCD with paraneoplastic pemphigus.Two patients of mediastinal UCD showed well defined centrilobular nodules in the lung.Eight patients of MCD mainly showed multiple small nodules,and large nodules with diameters of 1-2 cm were found in 2 of them.Four patients showed poorly defined nodules,and the rest 4 showed well-defined nodules.The nodules were mainly demonstrated as small centrilobular nodules,and a few of them located in subpleural regions in 3 patients.Other CT signs included interlobular septal thickening in 4 patients,ground glass opacity in 4 patients,streaks in 4 patients,patchy consolidation in 3 patients,cysts in 2 patients and thickening of the bronchovascular bundles in 1 patient.Conclusion CT manifestations of the lung in CD patients are complex and variable,and might be related to pathological types.