Comparison of CT features and pathology in multifocal lung adenocarcinoma with ground glass opacity
10.13929/j.1003-3289.201704117
- VernacularTitle:磨玻璃结节样多灶性肺腺癌CT征象与病理对照
- Author:
Yueyue LI
1
;
Xuemao LUO
;
Xin ZHANG
;
Ping CHEN
;
Yong LAN
;
Wansheng LONG
Author Information
1. 中山大学附属江门医院放射科
- Keywords:
Lung neoplasms;
Adenocarcinoma;
Tomography,X-ray computed;
Ground glass opacity
- From:
Chinese Journal of Medical Imaging Technology
2018;34(1):60-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate CT features of multifoeal lung adenocarcinoma (MLA) with ground glass opacity and the relationships with pathology.Methods Totally 16 cases (36 lesions) of MLA confirmed by pathology were collected.Based on pathology,the lesions were divided into pre-invasive lesion group (n =7),minimally invasive adenocarcinoma (MIA) group (n=20) and invasive adenocarcinoma (IAC) group (n =9).CT features of all three groups were analyzed and compared with pathology.Results Among 36 lesions,there were 19 lesions (52.78％) with round shape,19 (52.78％) with lobulation,12 (33.33％) with spiculation sign,13 (36.11％) with vacuole sign,12 (33.33％)with blood vessel cluster sign,and 32 lesions (88.89％) with well-defined interface.Seven pre-invasive lesions (7/7,100％) were all pure ground glass opacity (pGGO),while 12 lesions (12/20,60.00％) were pGGO in MIA group,other 8 lesions (8/20,40.00％) were mixed ground glass opacity (mGGO).Only 1 lesion (1/9,11.11％) in IAC group was pGGO,other 8 lesions (1/9,88.89％) were mGGO.There were significant differences of pGGO,spiculation sign,vacuole sign and blood vessel cluster sign among 3 groups (all P＜0.05).There were significant differences of pGGO,spiculation sign and blood vessel cluster sign between pre-invasive lesion and IAC group (P=0.001,0.003,0.001).Significant differences were found in spiculation sign,vacuole sign and blood vessel cluster sign between MIA and IAC group (P=0.014,0.014,0.001).Conclusion CT findings of multiple ground glass opacity are helpful to diagnosis of MLA before surgery.
