Ultrasound speckle tracking imaging in evaluation on left ventricular function in acute stage chest blast injury of rabbits
10.13929/j.1003-3289.201704041
- VernacularTitle:超声斑点追踪技术评估兔胸部爆震伤后急性期左心功能
- Author:
Xin ZENG
1
;
Dan DENG
;
Shimin LIANG
;
Xianmei LIU
;
Qian LI
Author Information
1. 西南医科大学附属医院超声科
- Keywords:
Speckle tracking imaging;
Chest;
Ventricular function,left;
Rabbits;
Wounds and injuries
- From:
Chinese Journal of Medical Imaging Technology
2018;34(1):10-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of chest blast injury on left ventricular function and myocardial strain with speckle tracking imaging (STI).Methods Fifty healthy New Zealand rabbits were randomly divided into 4 groups.Five rabbits without blast injury were used as a normal group,and the other rabbits were placed in specific semi-enclosed blasting environment in accordance with the different distance of the explosion.With instantaneous detonators,slight,medium and heavy chest blast injury animal models were produced and labeled as A,B,and C group (each n=15),respectively.The left ventricular function was measured with conventional echocardiography and STI.The longitudinal strain (LS) of the left ventricle was measured with two-dimensional strain analysis software and statistically analyzed.Results There was no significant difference of ejection fraction (EF) and fractional shortening (FS) in the left ventricle after chest blast injury between group A and normal group (all P＞0.05),while LS of anterior wall,anterior septum wall and lateral wall of group A significantly decreased compared with those of normal group (all P＜0.05).In group B and C,the left ventricular EF,FS and LS of each segment were lower than those of normal group (all P＜0.05).In group C,the left ventricular EF,FS and LS of each segment were lower than those in group A (all P＜0.05).There was no significant difference of EF and FS between group B and group C.In group C,LS of anterior wall and lateral wall of basal segment and middle segment were lower than those of group B (all P＜0.05).Conclusion STI can reflect functional changes of left ventricle in each segment earlier and more sensitively after chest blast injury.
