Research progress of stem cells and gene therapy for erectile dysfunction

VernacularTitle:干细胞及基因治疗勃起功能障碍的研究进展
Author: Lei WANG ^{1
,

2} ; Mingzong YUE ; Guangzhou CHENG ; Yuxi SHAN
Author Information

1. 277500 山东省滕州,济宁医学院附属滕州市中心人民医院泌尿外科
2. 215000 苏州大学附属第二医院泌尿外科
Keywords: Erectile dysfunction/TH; Stem cell transplantation; Gene therapy; Review
From: Journal of Chinese Physician 2018;20(10):1597-1600,封3
CountryChina
Language:Chinese
Abstract: Erectile dysfunction (ED) is a highly prevalent health problem with considerable impact on the quality of men and their partners.There are many drawbacks in the existing ED treatment.Stem cells have the function of self-renewal and differentiation into various cell types.Gene therapy mainly focuses on the regulation of various transmitters and enzymes in nitricoxide synthase/cyclic guanosine monophosphate (NOS/c GMP) pathway,growth factors,peptides and channel proteins,which make them have broad application prospects in the field of ED treatment.In recent years,stem cell and gene therapy of ED have achieved initial results.This article aims to review the latest research progress in this field.