Advances in the pathogenesis of long non-coding RNA in glioma
10.3760/cma.j.issn.1008-1372.2018.10.048
- VernacularTitle:长链非编码RNA影响胶质瘤发病机制的研究进展
- Author:
Xiaozhi LI
1
;
Junhong GUAN
Author Information
1. 中国医科大学附属盛京医院神经外科
- Keywords:
RNA,untranslated;
Glioma;
Review
- From:
Journal of Chinese Physician
2018;20(10):1590-1593
- CountryChina
- Language:Chinese
-
Abstract:
Glioma is one of the most common intracranial tumors.Long non-coding RNA(lncRNA) cannot be translated into proteins but has many important effects on bio-functions and diseases of human beings.The functions of lncRNA includes epigenetic regulation,transcription regulation,lncRNA-miRNA interation,being precursor of miRNA and these functions play important role in pathogenesis of glioma,lncRNA has many regulatory effects on the proliferation,invasion and metastasis of glioma cells,and plays a guiding role in the diagnosis and treatment of glioma.lncRNA influence the proliferation,migration and invasion of glioma and the study of lncRNA mean a lot in the treatment of patients with glioma.