The value of high resolution diffusion-weighted imaging in adolescent primary osteosarcoma
10.3760/cma.j.issn.1008-1372.2018.10.014
- VernacularTitle:高分辨率扩散加权成像在青少年原发性骨肉瘤中的价值研究
- Author:
Junjiao HU
1
;
Yanyu LI
;
Huabing LI
Author Information
1. 中南大学湘雅二医院放射科
- Keywords:
Osteosarcoma/DI;
Diffusion magnetic resonance imaging;
Adolescent
- From:
Journal of Chinese Physician
2018;20(10):1495-1497,1501
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of high resolution diffusion weighted imaging (RESOLVE-DWI) in adolescent primary osteosarcoma,and to compare the difference of image quality and apparent diffusion coefficient (ADC) value with conventional DWI echo planar imaging (EPI)-DWI.Methods Siemens Skyra 3.0T superconducting magnetic resonance imaging (MRI) scanner was used to collect MRI images of 30 patients suspected to be adolescent primary osteosarcoma.RESOLVE-DWI EPIDWI was performed.Meanwhile,the signal-to-noise (SNR) and ADC values of osteosarcoma tissues were measured and compared with the final pathological examination results.The image quality scores,SNR and ADC values of different diffusion weighted imaging sequences were tested by two independent samples t test.Results The overall quality of RESOLVE-DWI sequence images was significantly better than that of EPIDWI diffusion images,including 23 patients with RESOLVE-DWI scores ≥ 4 scored and 1 patients with EPI-DWI scores≥ 4,with significant difference(P ＜ 0.01).The mean ADC values of osteosarcoma tissues in RESOLVE-DWI sequence group and EPIDW sequence group were(856.16 ± 21.06) × 10-3 mm2 and (824.49 ±33.45) × 10-3 mm2,with no significant difference (P ＞0.05).The average SNR of RESOLVEDW1 group was significantly higher than that of EPI-DW1 sequence group (3.77 ± 0.51 vs 1.97 ± 0.23,P ＜ 0.01).Conclusions RESOLVE-DWI can improve the image quality and the SNR,and the ADC value of osteosarcoma tissue is not affected.It can provide more valuable diagnostic efficacy for the diagnosis of primary osteosarcoma in adolescents,and can be routinely used in the scanning of primary osteosarcoma in adolescents.
