The clinical value of intracranial translucency (IT) in open spina bifida at 11-13 +6 weeks of gestation

VernacularTitle:孕11～13+6周胎儿颅内透明层在开放性脊柱裂的诊断价值分析
Author: Guanghua XIANG ¹ ; Ling XU ; Dan QI ; Yanfang LIN ; Xiangying TIAN ; Yongdong LIANG
Author Information

1. 广东省妇幼保健院超声诊断科
Keywords: Spina bifida cystica/US; Ultrasonography,prenatal; Nuchal translucency measurement
From: Journal of Chinese Physician 2018;20(7):1039-1041
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical value of intracranial translucency (HT) in open spina bifida at 11-13 +6 weeks of gestation.Methods Abdominal ultrasound was performed in 200 cases of normal fetus and 6 cases of confirmed open spina bifida at 11-13 +6 weeks of gestation to compare the morphology of IT,diencephalon and midbrain.Results Fetal IT was readily recognized in all 200 normal cases,with diencephalons and midbrain showing number "8" shape.In 6 cases of open spina bifida,fetal IT cannot be identified,and the expected " 8" shape of diencephalon and midbrain was distorted.During 11-13 +6 weeks of pregnancy,the fetal brain is caused by intracranial negative pressure,resulting in morphological changes in the intracranial hyaline,diencephalon and mesencephalon.Conclusions Fetal brain characteristics including intracranial translucency and the shape of diencephalon and midbrain in 11-13 +6 weeks gestation are valuable ultrasound screening indicators for opens pina bifida.