Research progress of human glioma angiogenesis
10.3760/cma.j.issn.1008-1372.2018.06.047
- VernacularTitle:神经胶质瘤血管生成的研究进展
- Author:
Tianyao GUO
1
;
Tingting CHENG
;
Xianquan ZHAN
Author Information
1. 中南大学湘雅医院卫生部肿瘤蛋白质组学重点实验室、结构生物学与药物设计湖南省工程实验室、抗癌药物国家地方联合工程实验室
- Keywords:
Glioma;
Neovascularization,pathologic;
Proteomics;
Review
- From:
Journal of Chinese Physician
2018;20(6):954-960,封3
- CountryChina
- Language:Chinese
-
Abstract:
Tumor angiogenesis is the important pathophysiological characteristics of human glioma.The treatment of tumor angiogenesis is currently a hot research topic.This article reviewed the domestic and international research on angiogenesis of glioma,included animal models,cellular mechanisms,regulatory factors,signaling pathways,antiangiogenic drugs,and proteomics regarding glioma angiogenesis to clarify the current status of research and clinical treatment,providing reference for further study on angiogenesis of glioma,and discovery of novel biomarkers of tumor angiogenesis and therapeutic targets.
