Research progress in regulatory mechanism of CCAT2 and the relationship with digestive system neoplasm
10.3760/cma.j.issn.1008-1372.2018.05.051
- VernacularTitle:结肠癌相关转录子2的调控机制及与消化系统肿瘤关系的研究进展
- Author:
Jinglin LI
1
;
Zhenglong LI
;
Lining HUANG
;
Kaiming LENG
;
Daolin JI
;
Yi XU
;
Xingming JIANG
;
Yunfu CUI
Author Information
1. 150086,哈尔滨医科大学附属第二医院胆胰外科
- Keywords:
Digestive system neoplasms/GE;
RNA,long noncoding/GE;
Review
- From:
Journal of Chinese Physician
2018;20(5):790-793
- CountryChina
- Language:Chinese
-
Abstract:
Colon cancer associated transcript 2 (CCAT2) is found recently an important member of cancer-related long non-coding RNA (lncRNA).Dysregulation of CCAT2 plays a pivotal role in tumor pathophysiological processes,especially in tumourigenesis and progression of digestive system neoplasms,thus,CCAT2 likely represents a novel cancer biomarker or therapeutic target.Elucidation of the molecular mechanisms of CCAT2 will provide a feasible theoretical basis and potential interventional target for the diagnosis and treatment of malignancies.The present review summarizes current evidences of CCAT2 in digestive system neoplasms.
