The diagnostic value of ferritin, procalcitonin (PCT) and C-reactive protein (CRP) on infections disease

VernacularTitle:血清铁蛋白、降钙素原和C反应蛋白在感染性疾病诊断中的临床意义
Author: Yan WANG ¹ ; Xueying FU ; Lan HU ; Guangwei HUANG ; He WANG ; Chao WANG ; Wenjie QI
Author Information

1. 首都医科大学附属北京友谊医院感染内科
Keywords: Communicable diseases/DI; Ferritins/ME; Calcitonin/ME; C-reactive protein/ME
From: Journal of Chinese Physician 2018;20(5):661-663
CountryChina
Language:Chinese
Abstract: Objective To evaluate the diagnostic value of ferritin,procalcitonin (PCT) and C-reactive protein (CRP) on infectious diseases.Methods A total of 190 patients with infectious diseases in our hospital from 2012 to 2017 were enrolled and analysed retrospectively.Among them,bacterial infection was found in 130 cases (bacterial infection group),and viral infection in 60 cases (viral infection group).Serum levels of erritin,CRP,PCT in 190 patients were deteceted for further statistical analysis.Results Among the 190 cases of infectious fever,serum levels of erritin,CRP,PCT in bacterial infection group were higher than that in the viral infection group,with significant difference.The receiver operating curve (ROC) curve analysis showed that area under curve (AUC) of CRP,PCT,ferritin were 0.797,0.803,0.883.Conclusions The present study identified ferritin,PCT and CRP that should be considered in the differential diagnosis of infectious diseases,providing useful information for future diagnosis.