Xinjiang region the clinical characteristics and prognosis of tuberculous meningitis factor analysis
10.3760/cma.j.issn.1008-1372.2018.01.026
- VernacularTitle:新疆地区结核性脑膜炎的临床特点和预后因素分析
- Author:
Xinxin BU
1
;
Cuihuan ZHU
;
Xinglu WANG
;
Yuexin ZHANG
;
Xiaofeng SUN
Author Information
1. 新疆医科大学第一附属医院感染中心
- Keywords:
Tuberculosis,meningeal/DI/TH/EP;
Prognosis
- From:
Journal of Chinese Physician
2018;20(1):103-106
- CountryChina
- Language:Chinese
-
Abstract:
Objective To describe the Xinjiang region of tuberculous meningitis (TBM) (age ＞ 18 years of age) in patients with the clinical features,analysis of factors influencing the prognosis.Methods A retrospective of cases included in the data collection,describe the clinical characteristics,using the single factor and multiple factors Logistic regression analysis of factors influencing the prognosis.Results A total of 200 cases of TBM patients had the following characteristics:120 cases of male,female 80 cases;age 18 -75 (37.35 ±+ 14.24) years old;the course of the disease 3-270 (36.86 +43.86)days;and 179 cases of survival,21 cases of death,with a mortality of l0.5％.Single factor analysis showed that hydrocephalus,encephaledema,clinical staging,erythrocyte sedimentation rate,cerebro-spinal fluid (CSF)-protein had statistically significant difference between survival group and death group,respectively (P ＜ 0.05).The multi-factor Logistic regression analysis showed that encephaledema and erythrocyte sedimentation rate were independent factors to affect the prognosis of TBM (P ＜ 0.05).Conclusions Encephaledema and erythrocyte sedimentation rate are independent risk factors of poor prognosis in patients with TBM,early identify predictors,formulate corresponding clinical countermeasures,and can improve the prognosis of patients with tuberculous meningitis.
