The clinical characteristics and risk factors of frozen gait in Parkinson's disease

VernacularTitle:帕金森病冻结步态临床特征及相关因素研究
Author: Xun ZHOU ^{1
,

2} ; Qiying SUN ; Jifeng GUO ; Qian XU ; Yun TIAN ; Xinxiang YAN ; Beisha TANG
Author Information

1. 410008 长沙,中南大学湘雅医院神经内科
2. 410008 长沙,中南大学湘雅医院国家老年疾病临床医学研究中心
Keywords: Parkinson disease/CO; Gait apraxia/CO
From: Journal of Chinese Physician 2018;20(1):35-37,41
CountryChina
Language:Chinese
Abstract: Objective o investigate the clinical characteristics and relevant risk factors of freezing gait in patients with Parkinson's disease (PD).Methods A total of 570 consecutive PD patients were registered basic information and evaluated by Unified Parkinson's Disease Rating Scale (UPDRS) and New Freezing of gait questionnaire (NFOG-Q).They were divided into the PD with freezing gait group (188 cases) and non-freezing gait group.Results UPDRS score in each part (UPDRS-Ⅰ,UPDRS-Ⅱ,UPDRS-Ⅲ,UPDRS-Ⅳ) and Hoehn & Yahr stage of the PD freezing gait group was significantly higher than that of the non frozen gait group (P ＜ 0.05).Conclusions PD patients with frozen gait group experience more rapid PD progression than those without freezing of gait.The appearance of FOG is associated with the mental behavior and emotion,treatment complication,disease severity,and course of PD.