Influence of δ-opioid receptor in the central nervous system
10.3760/cma.j.issn.1008-1372.2018.01.008
- VernacularTitle:δ-阿片受体在中枢神经系统中的作用
- Author:
Si TENG
1
;
Tao CHEN
;
Yidong DENG
;
Yanhui LIU
;
Shan ZHANG
;
Jiali SU
;
Benchi CAI
Author Information
1. 海南省人民医院神经内科
- Keywords:
Receptors,opioid,delta;
Central nervous system;
Central nervous system diseases;
Review
- From:
Journal of Chinese Physician
2018;20(1):31-34
- CountryChina
- Language:Chinese
-
Abstract:
The delta-opioid receptor (DOR),which is a classic analgesic drug widely existed in the central system and peripheral system,is a kind of inhibitory G-protein coupled receptor with seven transmembrane regions.In addition to pain modulation,the opioid receptors are involved in various physiological and pathological activities through gene or cytokines.This review addresses the influence and possible mechanisms of the delta-opioid receptor in ischemic brain injury,analgesia,anti-anxiety and depression,learning and memory,and Parkinson's disease.
