Research progress of the structure, function and mechanism of Sestrin
10.3760/cma.j.issn.1008-1372.2017.12.052
- VernacularTitle:Sestrin的结构、功能及其作用机制研究进展
- Author:
Kejia WANG
1
;
Huina WANG
;
Xiaoqiang LI
;
Fu HAN
;
Yang LIU
;
Dahai HU
Author Information
1. 710032 西安,第四军医大学西京医院全军烧伤中心,烧伤与皮肤外科
- Keywords:
Heat-shock proteins;
Stress;
Review
- From:
Journal of Chinese Physician
2017;19(12):1912-1915
- CountryChina
- Language:Chinese
-
Abstract:
Sestrins is a stress-induced protein family, which is characterized by increased expres-sion in disease or stress, and plays its role in anti-inflammation, anti-oxidation and anti-aging, but its spe-cific molecular mechanisms and signal pathways are very complex. This review summarizes the related re-searches on sestrin in the past few years, and analyzes its specific functions and recent research progress in combination with its molecular structure.