Treatment of atherosclerosis obliterans in lower extremity with drug-coated balloon
10.3760/cma.j.issn.1008-1372.2017.12.007
- VernacularTitle:药物涂层球囊治疗下肢动脉硬化闭塞症
- Author:
Lixing QI
1
;
Yongquan GU
;
Lianrui GUO
;
Shijun CUI
;
Zhu TONG
;
Shengjia YANG
;
Yixia QI
Author Information
1. 100053 北京,首都医科大学宣武医院血管外科,首都医科大学血管外科研究所
- Keywords:
Balloon dilatation;
Drug-eluting stents;
Arteriosclerosis obliterans/SU;
Lower extrem-ity/PA
- From:
Journal of Chinese Physician
2017;19(12):1782-1785
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical outcome of drug-coated balloon ( DCB) treated atherosclerosis obliterans ( ASO) in lower extremity. Methods Data of 28 patients were retrospectively an-alyzed to determine the effectiveness and characteristics of DCB treatment. Results All the 28 patients were successfully treated with endovascular intervention therapy. Lesions mainly located in the superficial femoral arteries were divided into Groups A, B, C, and D according to TransAtlantic InterSociety Consensus (TASC) Ⅱ classification. Follow-up at 6, 9, and 12 months showed 100％, 84. 6％ and 76. 9％ patency rate in treated artery. After 9 months of endovascular intervention therapy, the combined artery patency rates in Groups A and B was 92. 8％, which was significantly better than 66. 7％ in Groups C and D ( P <0. 05 ) . DCB angioplasty had an artery patency rate of 86. 7％, while DCB angioplasty plus stenting had the patency rate of 85. 7％ (P>0. 05). Artery patency rate of Simple DCB angioplasty in ten patients (Exclu-ding patients with in-stent restenosis ) was 80％ and of Atherectomy plus DCB angioplasty in 5 patients was 100％ (P<0. 05). Conclusions DCB angioplasty has superiority over conventional intervention therapy. Combined debulky and DCB angioplasty appear to be the best choice in current treatment of ASO in lower extremity.
