Quality Standard Improvement for Funing Granules
- VernacularTitle:妇宁颗粒的质量标准的提高
- Author:
Jingyun LI
1
;
Qin WEN
;
Jieying GAO
;
Ruilian LI
Author Information
1. 湖南省药品检验研究院 湖南药用辅料检验检测中心 长沙410001
- Keywords:
Funing granules;
Quality standard;
TLC;
HPLC;
Paeoniflorin
- From:
China Pharmacist
2018;21(10):1883-1887
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To improve the quality standard of Funing granules. Methods: TLC was used for the qualitative identifica-tion of Angelicae Sinensis Radix, Chuangxiong Rhizoma, Scutellariae radix, Atractylodis macrocephalae rhizoma, Citri reticulatae peri-carpium, Cyathulae radix, Paeoniae radix alba and Glycyrrhizae radix Et rhizoma. The content of paeoniflorin was determined by HPLC. Results: The TLC spots were clear and well-separated without any interference from the negative control. The linear range of paeoniflorin was 19. 23-2525. 18 ng(r=0. 999 9), the average recovery was 101. 88% ,and the RSD was 0. 62% (n=6). Conclu-sion: The method is simple and accurate with good reproducibility, and can be used for the quality control of Funing granules.
