Reflection and Outlook on the Current Analytical Methods for Aminoglycosides
10.3969/j.issn.1008-049X.2018.06.036
- VernacularTitle:氨基糖苷类抗菌药物分析方法的思考及展望
- Author:
Yanghui ZHANG
1
,
2
;
Menghong JIANG
;
Feng QIN
;
Hao LIU
Author Information
1. 中国医药工业研究总院 上海201203
2. 上海市食品药品检验所
- Keywords:
Aminoglycosides;
ELSD;
PAD;
Post-column derivatization
- From:
China Pharmacist
2018;21(6):1082-1085,1089
- CountryChina
- Language:Chinese
-
Abstract:
The determination methods for the related substances and contents of aminoglycosides were reviewed. The HPLC-ELSD, HPLC-PAD and the other methods for the determination of aminoglycosides in Chinese Pharmacopoeia, USP and European Pharmacopoeia were introduced. The utilization specialties of the post column derivatization in detecting aminoglycosides were also in-troduced. Finally, the above three methods were compared, and the development of analytical methods for aminoglycosides was out-looked.
