Research Progress in the Antitumor Effects of Sulfated Polysaccharides
10.3969/j.issn.1008-049X.2018.06.035
- VernacularTitle:硫酸化多糖抗肿瘤研究进展
- Author:
Maolin ZENG
1
;
Benhong ZHOU
;
Xianxi GUO
Author Information
1. 武汉大学人民医院 武汉430060
- Keywords:
Polysaccharides;
Sulfation;
Tumor;
Research progress
- From:
China Pharmacist
2018;21(6):1078-1082
- CountryChina
- Language:Chinese
-
Abstract:
Sulfated polysaccharides are with hydroxyl group containing sulfate radicals, which can be obtained by natural extraction or chemical modification of sulfation. Recent studies have shown that sulfated polysaccharides exhibit different levels of antitumor activ-ity, especially in comparison with those before chemical modification; therefore, they have attracted wide attention. This article briefly reviewed the domestic and foreign researches on the antitumor effects of natural sulfated polysaccharides and chemical synthesized sul-fated polysaccharides in recent years.