Analysis on the Application of Proton Pump Inhibitors in 31 Hospitals in Wuhan Area from 2014 to 2016
10.3969/j.issn.1008-049X.2018.06.022
- VernacularTitle:2014~2016年武汉地区31家医院质子泵抑制药的使用情况分析
- Author:
Pan LUO
1
;
Chengliang ZHANG
;
Dong LIU
;
Xiang XU
Author Information
1. 华中科技大学同济医学院附属同济医院药学部 武汉430030
- Keywords:
Proton pump inhibitors;
DDDs;
DDC;
Drug utilization
- From:
China Pharmacist
2018;21(6):1037-1040
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the application characteristics of proton pump inhibitors (PPIs) in 31 hospitals in Wuhan ar-ea from 2014 to 2016 to provide reference for the clinical rational use. Methods: The utilization of PPIs in 31 hospitals in Wuhan area from 2014 to 2016 was statistically analyzed by drug types and dosage form in terms of consumption sum, DDDs, DDC, and consump-tion ranking (B)/DDDs ranking (A), etc. Results: The consumption sum and DDDs of PPIs were rising year by year. As for the dos-age form, the most commonly used one was oral preparation, however, the percent of injection kept high level. Among the different PPIs, oral poptolazole and lansorazole for injection were with the fastest increase in consumption sum and DDDs, while the consumption sum and DDDs of omeprazole for injection significantly decreased. The DDDs of oral poptolazole ranked first in the continuous three years with the B/A value much higher than 1. 0. The synchronicity was good for most of PPIs and the DDC was decreasing year by year. Moreover, PPIs were dominated by domestic products except for esomeprazole. Conclusion: The use of PPIs in 31 hospitals in Wuhan area from 2014 to 2016 was basically reasonable. However, some potential irrational application in clinic may still exist. There-fore, the application monitoring for PPIs should be further strengthened to promote rational drug use in clinics.
