Analysis of 400 New and Serious Adverse Drug Reactions in a Grade Three Class A Hospital
10.3969/j.issn.1008-049X.2018.06.019
- VernacularTitle:某三级甲等医院400例新的及严重的药品不良反应分析
- Author:
Hehuan SUI
1
;
Qiang SU
;
Lisha ZHU
;
Haixia ZHAO
;
Siyun YANG
Author Information
1. 南充市中心医院 川北医学院第二临床医学院临床药学科 四川南充637000
- Keywords:
Adverse drug reactions;
Monitoring;
Report;
Safe medication
- From:
China Pharmacist
2018;21(6):1028-1031
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the characteristics of adverse drug reactions (ADRs) in a grade three class A hospital to provide reference for rational drug use and reduction of ADRs. Methods: The new and serious ADRs reported during 2014 and 2016 were sta-tistically analyzed in terms of the report type, age, gender, administration route, drug variety and involving system. Results: The new and serious ADR reports reached to 400 cases, which accounted for 64. 52% of the total reports. Of the 400 ADR reports,there were 34. 25% distributed in the 60-74-year old. The proportion of male and female in the ADRs was basically equal, while that of male (50. 25% ) was slightly higher than that of female (49. 75% ). There were 57. 00% of ADRs caused by intravenous administration, and 31. 25% caused by anti-infective drugs, in which cephalosporins accounted for the most (32. 00% ). The most common manifesta-tion of ADR was damage to skin and its appendages, which accounted for 33. 00% , followed by the damage to gastrointestinal system (15. 50% ) and hepatorenal function (14. 00% ). Conclusion: Great attention should be paid to monitoring and reporting ADRs in our hospital, and drugs should be rationally used so as to reduce the occurrence of ADRs.
