Analysis of Clinical Application and Adverse Reactions of Scopolamine Butylbromide Injection
- VernacularTitle:丁溴东莨菪碱注射液的临床应用与不良反应分析
- Author:
Lei ZHENG
1
;
Jing YANG
;
Yuyao GUAN
;
Chao SONG
Author Information
1. 山东省立第三医院 济南250031
- Keywords:
Scopolamine butylbromide;
High risk factors;
Adverse reaction;
Combined medication
- From:
China Pharmacist
2018;21(5):867-870
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate and analyze the clinical application and adverse reactions of scopolamine butylbromide injection to promote the rational use in clinics. Methods:Totally 3695 effective cases treated with scopolamine butylbromide injection were collected from January 2016 to July 2017, and the age, sex, cause of drug use, medication days, combined use, high risk factors, and names, types and clinical manifestations of adverse reactions induced by scopolamine butylbromide were classified and statistically analyzed. Results:The overall incidence of adverse reactions of scopolamine butylbromide was 0.22%. The drug use rate was 44.36% in high-risk patients. The incidence of adverse drug reactions in high-risk patients was 1.83%,and that in low-risk patients was 0.24%, and the difference was 7.63 times. Combined drug use was common, and 1.98% of the combined use had potential drug interactions. Conclusion:The requirements of drug instructions should be strictly followed,and high-risk patients and drug combination should be paid much attention in order to reduce the risk of adverse drug reactions and ensure the drug safety.
