Determination of Six Heavy Metals in Iron Filings and Ferric Ammonium Citrate by Atomic Absorption Spectrophotometry
10.3969/j.issn.1008-049X.2018.03.042
- VernacularTitle:原子吸收分光光度法测定铁屑和枸橼酸铁铵中6种重金属
- Author:
Zebing ZHU
1
;
Dewei ZHANG
;
Lamei MOU
;
Jie KANG
Author Information
1. 重庆万州食品药品检验所药品科 重庆404000
- Keywords:
Iron filings;
Ferric ammonium citrate;
Lead;
Cadmium;
Arsenic;
Mercury;
Copper;
Chromium;
Atomic absorption spectrophotometry
- From:
China Pharmacist
2018;21(3):512-515
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish an atomic absorption spectrophotometric method for the determination of 6 heavy elements in-cluding lead,cadmium,mercury, arsenic, copper and chromium in iron filings and ferric ammonium citrate in order to control the quality and ensure people's daily medicine safety.Methods:The determination method for lead,cadmium,chromium,copper,arse-nic and mercury was a graphite furnace method, a graphite furnace method, a graphite furnace method, a flame method, a hydride method and a cold steam absorption method,respectively. Results:The concentration of lead within the range of 0-50 ng·ml-1had a good linear relationship with the absorbance(r=0.999 8),and the average recovery was 98.9%(RSD=2.3%,n=6). The concen-tration of cadmium within the range of 0-4 ng·ml-1had a good linear relationship with the absorbance(r=0.999 1),and the average recovery was 90.5%(RSD=1.5%,n=6). The concentration of chromium within the range of 0-50 ng·ml-1had a good linear rela-tionship with the absorbance(r=0.999 7),and the average recovery was 96.1%(RSD=1.1%,n=6). The concentration of copper within the range of 0-800 ng·ml-1had a ood linear relationship with the absorbance (r=0.999 9), and the average recovery was 97.5%(RSD=1.2%,n=6). The concentration of arsenic within the range of 0-16 ng·ml-1had a good linear relationship with the absorbance (r=0.999 0),and the average recovery was 93.4%(RSD =1.1%, n =6). The concentration of mercury within the range of 0-18 ng·ml-1had a good linear relationship with the absorbance(r=0.999 2),and the average recovery was 93.2%(RSD=3.8%,n=6). Conclusion:The method with good repeatability is accurate,which can be used for the quality control of iron filings and ferric ammonium citrate.
