A Case of Large Cell Neuroendocrine Carcinoma of the Gallbladder.
- Author:
Young Hoon KIM
1
;
Ji Bong JEONG
;
Sae Kyung JOO
;
Min Young CHOI
;
Kook Lae LEE
;
Mee Soo CHANG
;
Young Joon AHN
Author Information
1. Department of Internal Medicine, Boramae Hospital, Seoul National University College of Medicine, Seoul, Korea. jibjeong@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Carcinoma;
Neuroendocrine;
Gallbladder
- MeSH:
Biopsy;
Carcinoma, Neuroendocrine;
Cholecystectomy;
Gallbladder;
Gallbladder Neoplasms;
Humans;
Laparoscopy;
Liver;
Lymph Node Excision;
Male;
Neoplasm Metastasis
- From:Korean Journal of Medicine
2013;85(2):183-187
- CountryRepublic of Korea
- Language:English
-
Abstract:
We herein report a case of large cell neuroendocrine carcinoma (NEC) of the gallbladder confirmed by laparoscopic surgery. A 60-year-old male was HBsAg-positive. Abdominal computed tomography showed a 2.5 x 2.5 cm enhancing polypoid mass in the gallbladder and multiple masses in liver segments 4 and 5 that enhanced in the arterial phase and washed out in the delayed phase. Liver biopsy findings showed only poorly differentiated morphology. A laparoscopic operation was performed for diagnosis of the masses because curative resection seemed impossible to perform, which showed unusual findings of either hepatocelluar carcinoma or gallbladder cancer. Therefore, laparoscopic liver biopsy and cholecystectomy were performed. The final pathologic results of the masses showed large cell NEC of the gallbladder with liver metastasis. Central bisegmentectomy and extensive lymph node dissection were ultimately performed. The patient was still alive 16 months after diagnosis.
