Study on the Chemical Components in the Rattan of Rubia Argyi L.
10.3969/j.issn.1008-049X.2018.03.002
- VernacularTitle:东南茜草藤的化学成分研究
- Author:
Xiangqin SHI
1
;
Guoxu MA
;
Hong ZHANG
;
Rong HUANG
;
Ling HAN
;
Maoting ZHANG
;
Yaoru ZHANG
;
Xudong XU
;
Shichun YU
;
Shoujin LIU
Author Information
1. 安徽中医药大学药学院 合肥230012
- Keywords:
Rattan of Rubia argyi L.;
Rubiaceae;
Chemical components
- From:
China Pharmacist
2018;21(3):380-384
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the chemical constituents in the rattan of Rubia argyi L.. Methods:The air-dried rattan of Rubia argyi L. was powdered and extracted three times by 75% ethanol with refluxing. After removing the solvent under the reduced pressure,the crude extract was dissolved in water,and then filtrated and extracted by petroleum ether and ethyl acetate to obtain crude extract after removing petroleum ether and ethyl acetate. The compounds were isolated and purified by silica gel column chromatogra-phy,reversed-phase silica gel column chromatography and Sephadex LH-20 gel column chromatography,and then identified based on physicochemical properties and spectral analysis(1 H-NMR and 13C-NMR). Results:Totally 13 compounds were isolated from the rat-tan of Rubia argyi L.,and characterized as secoisolariciresinol(1),xanthopurpurin(2),daucosterol(3),dehydroabietic acid(4), 2-hydroxy-1-methoxy-anthraquinone(5),β-sitosterol(6),lirioresinol A(7),2-hydroxy-7-methyl-9,10-anthraquinone(8),strych-novoline (9), ciwujiatone (10), 3,4-divanillyltetrahydrofuran (11), 2-(4-hydroxypheny) -6-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3,3,0]octane (12), and (6S,9R)-vomifoliol (13).Conclusion: The compounds 1-13 are isolated from the rattan of Rubia argyi L. for the first time and the compounds 1,2,4,5 and 7-13 are first isolated from Rubia L..
