Improvement of Quality Standard forAidi B Capsules
- VernacularTitle:爱迪胶囊B质量标准的提高
- Author:
Chao ZHAO
1
;
Yan LI
;
Xiaodan BAI
;
Zhifu YANG
;
Aidong WEN
;
Jinyi CAO
Author Information
1. 空军军医大学第一附属医院药学部 西安710032
- Keywords:
Aidi B capsule;
Quality standard;
HPLC;
TLC
- From:
China Pharmacist
2018;21(2):351-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the quality standard for Aidi B capsules.Methods:Astragalus membranaceus,Fallopia multi-flora and Gastrodiae elata were identified by TLC qualitatively.The content of gastrodin was determined by HPLC.The chromatographic separation was carried out on an Eclipse Plus C18column (250 mm ×4.6 mm,5 μm). The mobile phase consisted of acetonitrile-0.05% phosphoric acid solution (2:98) at a flow rate of 1.0 ml·min-1.The detection wavelength and the column temperature was 220 nm and 25℃,respectively.Results:The spots in TLC were clear without any interference.The linear range of gastrodin was 8.532-208.8 μg·ml-1(r=1.000 0),and the average recovery was 100.30%(RSD=0.37%,n=6).Conclusion:The method is simple with good repeatability,which can be used for the quality control of Aidi B capsules.
