Application of Chitosan and its Derivatives in Drug Carriers
- VernacularTitle:壳聚糖及其衍生物在药物载体中的应用
- Author:
Hairong WANG
1
,
2
,
3
;
Hongyu JI
;
Jiayu FENG
;
Chengcheng ZHANG
;
Linhua WU
Author Information
1. 哈尔滨医科大学附属第二医院药学部 哈尔滨150086
2. 哈尔滨医科大学药学院
3. 黑龙江省高校重点实验室
- Keywords:
Chitosan;
Derivative;
Drug carrier;
Application
- From:
China Pharmacist
2018;21(2):324-327
- CountryChina
- Language:Chinese
-
Abstract:
Chitosan and its derivatives with good characteristics such as non-toxicity,good biocompatibility and degradability,mu-cosal adhesion and permeability promotion etc,have been widely researched and applied in the field of drug carriers. Based on the re-cently published papers at home and abroad,the application and action mechanism of chitosan and its derivatives as drug carriers were analyzed and discussed,and the application and research progress of chitosan and its derivatives as anti-tumor drug targeting carriers, sustained-release and controlled-release drug carriers,ophthalmic drug carriers,gene carriers and gel bases were reviewed.
