Analysis on Application Rationality of Proton Pump Inhibitors in 880 Patients Undergoing Operation in Gy-necology Department
- VernacularTitle:880例妇科手术患者应用质子泵抑制剂合理性分析
- Author:
Jianjie CHU
1
;
Weiwei LI
;
Yanhua WANG
;
Wei ZHANG
;
Dongmei HU
;
Zeqiong NING
;
Xian ZHAO
;
Yi QIAO
;
Jingwen WANG
;
Aidong WEN
Author Information
1. 第四军医大学第一附属医院药剂科 西安710032
- Keywords:
Proton pump inhibitors;
Stress ulcer;
Patients with surgery;
Rational drug use
- From:
China Pharmacist
2018;21(2):260-263
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the use of proton pump inhibitors (PPIs)in gynecological patients in a hospital and analyze the use rationality of PPIs for the prevention of stress ulcer so as to provide reference for the clinical application of PPIs. Methods:To-tally 1000 patients' medical records admitted to the gynecological department for the first time from January 1st to December 31st in 2016 were randomly selected to conduct a retrospective analysis,and the rationality of PPIs was evaluated. Results:The preventive use rate of PPIs was 90.72%(880/970). Among the 880 patients, 28.18%(248/880) of the patients were without indications for the preventive medication,95.68%(842/880) of the patients were with wrong administration time, and 91.46%(578/632) of the pa-tients were with wrong usage and dosage. Conclusion:When PPIs are used for the prevention of SU in gynecological surgery,irrational use such as without indications, unsuitable variety selection and wrong usage and dosage still exists. It is suggested that regulators should strengthen technical and administrative interventions and establish standard for the rational use of PPIs in hospitals so as to avoid the excessive use of PPIs and improve the situation of inappropriate application.
