Investigation on the Use of Oral High-risk Tablets in Hospitalized Patients in a Children's Hospital in Shanghai
- VernacularTitle:上海某儿童医院住院患者分剂量口服高风险片剂的使用调查
- Author:
Shiying HUANG
1
;
Fanghong SHI
;
Hao LI
;
Shunguo ZHANG
;
Wei ZHAO
;
Xuexian WANG
;
Anle SHEN
;
Bulong XU
;
Minling CHEN
Author Information
1. 上海交通大学医学院附属上海儿童医学中心药剂科 上海 200127
- Keywords:
High-risk;
Tablets;
Specification;
Sub-dose;
Children
- From:
China Pharmacist
2018;21(2):257-260
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the dosage distribution and the frequency of each dosage of high-risk tablets in the hospitalized patients in a children's hospital,and study whether the existing specifications of high-risk tablets meet the pediatrics clinical needs. Methods:All the prescriptions including high risk tablets were analyzed from 2014 to 2016 in Shanghai children's medical center. The frequency of every dosage of every drug was analyzed,and the current specifications were judged according to the frequency. New specifications were proposed when the existing specifications did not match the clinical needs. The new frequency of the proposed speci-fications was re-accounted for all the three-year prescriptions in order to evaluate whether the proposed new specifications met the clini-cal needs. Results:Among the five kinds of high-risk oral tablets,methotrexate tablets and vitamin A acid tablets were in accordance with the actual clinical requirements. Mercaptopurine tablets should add two specifications including 12.5 mg and 17 mg,and warfarin sodium tablets should add one specification(1.25 mg). Hydroxyurea tablets(250 mg) and warfarin sodium tablets(1 mg) were rec-ommended used in the children's hospital. Conclusion:The existing specifications of high-risk oral tablets can't fully meet the clini-cal needs,therefore,specifications still needs to be adjusted.
